Improving Care

Reducing morbidity and mortality and enhancing quality of life

Informing Policy

Transforming health care at the local, national and international levels

Featured Projects

With more than 80 scientists, research at Advancing Health encompasses a wide breadth of areas


The Evidence Speaks

A recurring feature highlighting the latest in Advancing Health research

Our People

In the News

Research Resources

From design to execution, Advancing Health provides a broad range of support services

Work in Progress Seminar Series

Loading Events

« All Events

  • This event has passed.

WiP Seminar: Thrombosis vs. Hemostasis

October 18, 2023 @ 12:00 pm 1:00 pm

Agnes Lee, MD, M.Sc.
Scientist, Advancing Health
Director, Thrombosis Program, VCH
Professor of Medicine, UBC

Thrombosis vs. Hemostasis: Balancing the competing risks of bleeding and clotting

Hemostasis is the physiological response to vessel injury that requires activation of the coagulation cascade. This is a highly complex and ‘self-regulating’ series of enzymatic reactions of zymogens that ultimately culminates in the formation of a stable clot. Unfortunately, an exuberant response can lead to pathological clotting or thrombosis. Other conditions that lead to thrombosis include venous stasis and hypercoagulable states that mobilize other physiological pathways and augment coagulation activation. To reduce thrombosis formation or extension, anticoagulant therapy is used to inhibit coagulation, and thereby necessarily renders the patient at risk for excessive bleeding when tissues and vessels are injured. Consequently, the ‘holy grail’ of finding the ideal anticoagulant has been focused on dissociating these competing risks of bleeding and clotting.

This is a virtual event, please register to receive Zoom link.



October 18, 2023
12:00 pm – 1:00 pm
Event Category: